Photodynamic application of protoporphyrin IX as a photosensitizer encapsulated by silica nanoparticles

olloidal mesoporous silica nanoparticles with rotoporphyrin IX encapsulated for photodynamic herapy

un Qian rash Gharibi ailing He hejiang University oint Research Center of Photonics of the Royal Institute of Technology Sweden and hejiang University entre for Optical and Electromagnetic Research ijingang Campus, Hangzhou 310058 hina Abstract. Protoporphyrin IX PpIX -encapsulated mesoporous silica nanoparticles were synthesized, characterized, and utilized for photodynamic therapy PDT of canc...

Photodynamic action of protoporphyrin IX derivatives on Trichophyton rubrum.

BACKGROUND Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacked and development of antifungal resistance in these microorganisms. In this context, Photodynamic Therap...

Evaluation of Sonochemiluminescence in a Phantom in the Presence of Protoporphyrin IX Conjugated to Nanoparticles

Introduction When a liquid is irradiated with high-intensity and low-frequency ultrasound, acoustic cavitation occurs and there are some methods to determine and quantify this phenomenon. The existing methods for performing these experiments include sonochemiluminescence (SCL) and chemical dosimetric methods. The particles in a liquid decrease the ultrasonic intensity threshold needed for cavit...

preparation and characterization of sub-150 nm protoporphyrin ix-loaded nanoparticles for photodynamic therapy

APOPTOSIS INDUCTION BY PHOTODYNAMIC TREATMENT WITH ENDOGENOUS PROTOPORPHYRIN IX? Short title: Apoptosis by ALA-PDT?

v Apoptosis can be induced in several cell lines by photodynamic treatment with different photosensitizers including aminolevulinic acid (ALA)-stimulated endogenous protoporphyrin IX (PpIX). This PpIX is successfully used as tumor marker in diagnosis, and owns good sensitizing properties for tumor therapy (PDT). The aim of the study was to investigate cell death mechanisms and its consequences ...